Table 3 Comparison of kinetic and thermodynamic parameters describing β1 integrin interaction with T3SA+ reovirus disassembly intermediates.
From: Reovirus directly engages integrin to recruit clathrin for entry into host cells
Mn2+ | Virion | Virion + Neu5Ac | ISVP | CORE |
|---|---|---|---|---|
BF [%] | 19 ± 7 | 6 ± 2 | 4 ± 2 | 19 ± 5 |
koff [s-1] | 0.4 ± 0.2 | 0.57 ± 0.1 | 0.59 ± 0.3 | 1.52 ± 0.4 |
kon [µM-1 s-1] | 5.83 ± 0.6 | 4.92 ± 1.06 | 5.62 ± 0.1 | 2.05 ± 0.3 |
KD [nM] | 68 ± 56 | 116 ± 45 | 105 ± 81 | 741 ± 317 |
xu [nm] | 0.69 ± 0.07 | 0.41 ± 0.02 | 0.50 ± 0.04 | 0.74 ± 0.03 |
