Fig. 8: A hypothetical model for MREL57-WDL7 module function in stomatal closure in response to ABA.
From: The E3 ligase MREL57 modulates microtubule stability and stomatal closure in response to ABA
Working model for the role of WDL7 proteolysis in ABA-induced stomatal closure and microtubule disassembly in WT and mrel57 mutant guard cells. WDL7 is a microtubule-stabilizing protein. In WT, the E3 ligase MREL57 ubiquitinates and degrades WDL7 in response to ABA, which facilitates microtubule disassembly and stomatal closure. In mrel57 mutant, the degradation of WDL7 is blocked. WDL7 binds to and stabilizes microtubules, resulting in stomatal closure insensitivity to ABA in mrel57 mutant.
