Fig. 5: SELENOW upregulates osteoclast differentiation-related genes.
From: Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts
a, b Analysis of RNA-sequencing transcriptomic data. Osteoclast precursors from SELENOW−/− and SELENOW-transgenic mice and corresponding wild-type littermates were differentiated into osteoclasts in the presence of M-CSF and RANKL for 3 days. The relative fold change in the levels of genes in SELENOW−/− (a) and SELENOW-overexpressing osteoclasts (b) was determined. Source data are provided as a Source Data file.
