Fig. 4: Characterization of ICG loaded mitochondrion-specific dendritic lipopeptide liposomes ICG/L-G2R-DA.
From: Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery
a UV/Vis spectra of free ICG, ICG/L-TPP, ICG/L-G2R-SA, and ICG/L-G2R-DA in PBS. b Size distribution of ICG/L-G2R-DA in an aqueous solution of pH 7.4, pH 6.8, and 5.5 for 12 h measured by DLS. c Cryo-TEM image of ICG/L-G2R-DA. The scale bar is 200 nm. d The change of the zeta potential at different pH values. Data are presented as means ± SEM. (n = 3 independent samples). e Schematic illustration of acid cleavage of ICG/L-G2R-DA. f Photothermal temperature curves of ICG/L-G2R-DA at the various concentrations (2–25 μg/mL) and free ICG at high concentration (25 μg/mL) with different exposure times.
