Table 1 Summary of demographics, pathology, and cognitive skills for study groups.

From: Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Diagnosis

n

Age

Sex

PMI (h)

ADNC

mBADLS

Control

5

57.2 ± 4.9

4 M, 1 F

15.4 ± 4*

  

AD

5

57.8 ± 2.2

2 M, 3 F

3.8 ± 1

Stages VI, C

27.4 ± 13.7

DS

6

56.3 ± 3.5

3 M, 3 F

4.1 ± 1

Stages VI, C

33.2 ± 9.3

  1. Values for age, postmortem interval (PMI), and the modified version of the Bristol Activities of Daily Living Scale (mBADLS) are mean ± SD; individual values are presented in Supplementary Data 1. AD Neuropathologic Change (ADNC), Braak stage VI and CERAD stage C. PMIs were longer for the control group (*P < 0.05 versus AD and DS groups, Dunn’s Multiple Comparison test), but within a range that does not affect synaptic measures; See “Methods” for further details.
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