Table 2 Counts of excitatory and inhibitory synapses in superficial layers of parietal cortex.

From: Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Protein

Region

Control

AD

DS

1-way ANOVA

PSD-95

layer 1

24759 ± 534

24614 ± 577

26856 ± 1177

P = 0.1581, n.s.

PSD-95

layer 2

24455 ± 790

25012 ± 635

24863 ± 572

P = 0.8382, n.s.

GPHN

layer 1

27037 ± 590

25023 ± 1146

26353 ± 1065

P = 0.3885, n.s.

GPHN

layer 2

27148 ± 779

24660 ± 298

25224 ± 1361

P = 0.8499, n.s.

  1. Average counts (mean ± SEM) of immunoreactive synapses and statistical comparisons are shown. (n.s., not significant).