Table 1 Administered tFUS conditions with constant TBD.

From: Intrinsic functional neuron-type selectivity of transcranial focused ultrasound neuromodulation

tFUS conditionsa

PRF (Hz)

DC (%)

ISPTA (mW/cm2)

PRF 30 Hz

30

0.6

1.05

PRF 300 Hz

300

6

10.55

PRF 1500 Hz

1,500

30

52.74

PRF 3000 Hz

3,000

60

105.48

PRF 4500 Hz

4,500

90

158.22

  1. aExcept for the ultrasound pulse repetition frequency (PRF), the ultrasound duty cycle (DC), and the spatial-peak temporal-average intensity (ISPTA), all of the listed tFUS conditions keep the following parameters constant, i.e., ultrasound fundamental frequency (f0 = 500 kHz), ultrasound duration (UD = 67 ms), cycle per pulse number (CPP = 100), tone-burst duration (TBD = 200 µs), spatial-peak pulse-average intensity (ISPPA = 175.80 mW/cm2), and spatial-peak temporal-peak intensity (ISPTP = 351.61 mW/cm2). Note: the inter-sonication interval (ISoI) has a typical value of 2.5 s and has 10% jittering. This 10% jittering of the inter-stimulus interval is to minimize the timing effect and potential brain adaptation to the tFUS stimulation.
Back to article page