Fig. 1: Expression of ESGs in cancer cells and CAFs by scRNA-seq.
a Scheme depicting the gene selection and filtering process for defining cancer type-specific lists of EMT signature genes (ESGs). b Heatmaps showing expression levels of ESGs (rows) in cancer cells and CAFs (columns) in 4 scRNA-seq datasets (panels) out of the 8 considered (the remaining 4 are shown in Fig. S4). Columns (cells) are ordered by their EMT scores (see Methods), which are shown in the line graphs below the heatmaps. The bar above each heatmap shows the number of genes detected in each cell. c Heatmaps showing the average and 95th percentile of the expression levels of each of the core EMT TFs and Vimentin in cancer cells and CAFs in each of the 8 scRNA-seq datasets.
