Fig. 4: Predicting noxious-evoked response amplitudes from non-noxious data. | Nature Communications

Fig. 4: Predicting noxious-evoked response amplitudes from non-noxious data.

From: Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity

Fig. 4: Predicting noxious-evoked response amplitudes from non-noxious data.

For all plots, each blue dot represents an out-of-sample cross-validated prediction for a single neonate (n = 18), and the dashed grey line is the y = x line along which perfect predictions would lie. The x-axis is the observed noxious-evoked response amplitude (after cross-validated confound regression), and the y-axis is the predicted noxious-evoked response amplitude. Predictions were generated based on three sets of predictors: (left) the resting-state network amplitudes; (middle) resting-state imaging confounds, which included head motion, CSF amplitude, and white matter amplitude; and (right) clinical variables, which included age (gestational, postmenstrual, and postnatal), birth weight, total brain volume, and sex. Source data are provided as a Source Data file.

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