Fig. 4: Functional alterations in control, adenoma, and cancer.
From: Identification of microbial markers across populations in early detection of colorectal cancer
The relative abundances of functional pathways were compared between adenoma and control or cancer. Differentially abundant pathways were plotted; P values were computed using a two-sided blocked Wilcoxon rank-sum test and the exact P values < 0.05 were presented in the heatmap. Generalized fold change (see “Meta-analysis of differentially abundant ASVs” section) was indicated by color gradients. The generalized fold change > 0: enriched in the latter; generalized fold change < 0: enriched in the former. Source data are provided as a Source Data file.
