Fig. 4: Upstream circuits of Canon neurons. | Nature Communications

Fig. 4: Upstream circuits of Canon neurons.

From: Regulation of coordinated muscular relaxation in Drosophila larvae by a pattern-regulating intersegmental circuit

Fig. 4

a EM reconstruction of left side Canon neurons in neuromeres A2 and A3. b A bar graph showing percent of total postsynapses of A2–A3 Canon neurons that are targeted by the indicated upstream neuron. Major partners (occupying more than 5% of total postsynapses) are shown. c Serial EM images showing synapses between ThDN neuron (presynapse, orange) and A2 Canon neuron (postsynapse, light blue). White arrows indicate T-bars. The images show representative synapses of observed 30 synapses from ThDN to Canon neurons. d, e Dorsal (d) and anterior view (e) of reconstruction images of ThDNs (orange) and A2 Canon (blue) neurons. Triangles indicate the midline. f A diagram of connectivity from MDN to Canon neurons. Arrows with filled heads indicate cholinergic synapses while arrows with empty heads indicate synapses with unidentified neurotransmitter. The bar indicates inhibitory outputs. Numbers next to the lines show the number of synapses. Scale bar (c), 500 nm.

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