Fig. 7: Expression of EGF and FGF pathways components. | Nature Communications

Fig. 7: Expression of EGF and FGF pathways components.

From: A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

Fig. 7: Expression of EGF and FGF pathways components.

a Dot plot depicting expression of relevant EGF ligands and receptors in pooled 3D samples—PP-spheroids and fetal spheres—and fetal pancreas samples. b Expression of selected gene markers overlapped on the global UMAP showing AREG expressing cells enriched in the ductal cluster. c Dot plot depicting expression of FGF ligands and receptors in 3D samples—PP-spheroids and fetal spheres—and fetal pancreas. Color intensity indicates mean expression in a cluster, dot size indicates the proportion of cells in a cluster expressing the gene.

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