Fig. 4: Structure comparison between Hsp21 monomers from Hsp21-DXPS and the Hsp21 dodecamer.
From: Structural basis of substrate recognition and thermal protection by a small heat shock protein
a Side view of map segments fitted with the model of the Hsp21 monomer from Hsp21-DXPS (left, blue) and the Hsp21 dodecamer (right, magenta). The beta strands on one sheet of the ACDs are labeled for side-by-side comparison. Note the missing of the beta2 strand in the Hsp21 monomer (blue) derived from the Hsp21-DXPS complex. The DXPS binding, dimeric and non-dimeric interfaces of Hsp21 are labeled. b Superimposition of the two models viewed from different directions. For the side views, the back side of ACD was clipped for clarity. The β5-β7 loops and the CTRs on both monomers which they exhibit different conformations are labeled. Twisting of the beta sheets of the ACD from the Hsp21 dodecamer is revealed through overlay of the models (middle and right).
