Fig. 5: MAYV glycosylation sites may play a role in the interaction with the MXRA8 receptor. | Nature Communications

Fig. 5: MAYV glycosylation sites may play a role in the interaction with the MXRA8 receptor.

From: Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses

Fig. 5: MAYV glycosylation sites may play a role in the interaction with the MXRA8 receptor.The alternative text for this image may have been generated using AI.

The E1 and E2 monomers are shown as grey surface. The MXRA8 receptor surfaces were mapped in the MAYV cryo-EM structure by superposing the cryo-EM structure of murine MXRA8 in complex with CHIKV (PDBid 6NK624). The N141 (E1) and N262 (E2) glycosylation sites are highlighted by dashed lines and pointed. Top (left) and side (right) views are shown. The N262 handshake glycosylation site is located at the center of the MXRA8 interaction site and potentially participates in the interaction with the host MXRA8 receptor.

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