Fig. 2: Preparation and characterization of H@CaPP. | Nature Communications

Fig. 2: Preparation and characterization of H@CaPP.

From: Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy

Fig. 2: Preparation and characterization of H@CaPP.

a Schematic illustration of the preparation route of H@CaPP. b Particle size of CaPP, D@CaPP, and H@CaPP measured by dynamic light scattering. c Average diameter of CaPP, D@CaPP, and H@CaPP (mean ± SD, n = 3 samples per group). d Morphology of CaPP and H@CaPP. Scale bar, 50 nm. The experiments were repeated three times independently. e Surface zeta potential of CaPP, D@CaPP, and H@CaPP (mean ± SD, n = 3 samples per group). f The PP release profile of D@CaPP, H@CaPP, or PP in PBS (pH 7.4) at 37 °C with gentle stirring (mean ± SD, n = 3 samples per group). g Average size of D@CaPP and H@CaPP within 24 h incubation with 10% FBS or PBS (pH 7.4) at 37 °C, respectively. h Zeta potential of D@CaPP and H@CaPP incubated with 10% FBS or PBS (pH 7.4) at 37 °C, respectively within 24 h (mean ± SD, n = 3 samples per group). Error bars represent SD.

Back to article page