Fig. 8: H@CaPP inhibited the formation of a pre-metastatic microenvironment in vivo.
From: Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy
Representative images of immunohistochemical analysis of ICAM-1, VCAM-1, MMP-9, and S100A9 (brown) in the lung of breast tumor-bearing mice after intravenously administrated with saline, LMWH, piceatannol, CaPP, D@CaPP, or H@CaPP (i.v. at a dose of piceatannol or PP at 0.020 mmol/kg, at a dose of Dextran or LMWH at 10 mg/kg) for seven times in 14 days. Scale bar, 50 μm.
