Fig. 8: Development of a composite model to predict the belonging of a patient to one of the 4 clusters. | Nature Communications

Fig. 8: Development of a composite model to predict the belonging of a patient to one of the 4 clusters.

From: A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

Fig. 8: Development of a composite model to predict the belonging of a patient to one of the 4 clusters.

a Confusion matrix of the composite model in the discovery cohort performed for 227 pSS patients (C1: 79, C2: 60, C3: 66, and C4: 22) is shown. b Discriminant function analysis (DFA) of the predicted patients from the discovery cohort shows clearly separated clusters. Two different views of the same DFA are shown. c DFA of the predicted patients from the inception cohort shows clearly separated clusters. Two different views of the same DFA are shown. Thirty-seven pSS patients from the inception cohort were analyzed and predicted as C1: 16, C2: 6, C3: 7, and C4: 8.

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