Fig. 2: Chromosome copy number analysis.
From: Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci
The genomic sequences of twelve 5-FC resistant clones each from H99, R265, and WM276 were determined, and the copy number of each chromosome was calculated. The change of copy number is represented by the intensity of the color. The red color represents copy gain and blue color represents copy loss in units of log2 as shown by the color scale. The color bar represents the location of copy number change in the chromosome. The name of chromosome or contig is indicated at the bottom of each panel and the width of the column represents the size of chromosome or contig. The name of each clone is on the left side of each panel. The “L” and “S” in the name represent the size of the colony at the time of its isolation and ST and US in the suffix indicates the stability of each 5-FC resistant clone as either stable or unstable, respectively.
