Fig. 3: Substrate scope. | Nature Communications

Fig. 3: Substrate scope.

From: Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

Fig. 3: Substrate scope.The alternative text for this image may have been generated using AI.

Reversed hydroboration of β,β-disubstituted α,β-unsaturated amide. a5 mol% Rh catalyst. b7.5 mol% Rh catalyst, 3.5 equivalent of HBpin, 0 °C. The product was isolated after oxidation. c5 mol% Rh catalyst. The product was isolated after oxidation. d5 mol% Rh catalyst, 6.0 mol% (−)-DIOP. The product was isolated after oxidation. TIPS triisopropylsilyl, MOM methoxymethyl, TBDPS t-butyldiphenylsilyl.

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