Table 1 Univariable and multivariable analysis of overall survival according to HOXA13 or HOXA11-13 expression and select variables.
Univariate | Multivariate (HOXA13) | Multivariate (HOXA11-13) | |||||||
|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
HOXA13 expression (FPKM) ≥1 vs. <1 | 4.675 | 1.39–15.69 | 0.013 | 38.25 | 1.37–1071 | 0.032 | |||
HOXA11-13 expression (FPKM) ≥1 vs. <1 | 5.872 | 1.84–18.74 | 0.003 | 8.84 | 0.82–95.24 | 0.072 | |||
Gender Males vs. female | 1.13 | 0.42–3.01 | 0.806 | 0.959 | 0.05–17.78 | 0.978 | 0.89 | 0.066–12.015 | 0.93 |
Age Pediatric vs. adult | 0.21 | 0.07–0.64 | 0.006 | 0.154 | 0.006–3.684 | 0.248 | 0.34 | 0.014–8.444 | 0.512 |
WBC Low vs. high | 1.46 | 0.62–3.43 | 0.381 | 73.52 | 1.59–3390 | 0.028 | 31.95 | 1.5–680.5 | 0.0264 |
Hemoglobin | 1 | 0.99–1.02 | 0.571 | 1.02 | 0.94–1.11 | 0.574 | 1.008 | 0.94–1.077 | 0.813 |
Platelet | 1 | 0.99–1 | 0.952 | 0.986 | 0.968–1.004 | 0.127 | 0.987 | 0.971–1.004 | 0.139 |
Hepatosplenomegaly Yes vs. no | 1.47 | 0.34–6.33 | 0.605 | 0.24 | 0.004–15.882 | 0.504 | 1.67 | 0.022–128.414 | 0.817 |
Blasts in BM | 1.01 | 0.98–1.03 | 0.621 | 1.107 | 0.906–1.352 | 0.319 | 1.08 | 0.9–1.294 | 0.407 |
