Table 1 Summary of clades identified in dataset including intra-clade single nucleotide polymorphisms (SNP) distances, total counts of isolates and those with elevated cefixime (CFM) or ceftriaxone (CRO) minimum inhibitory concentrations (MICs), collection year, and predominant multi-locus sequence type (MLST).
No. of isolates with elevated MIC | ||||||
|---|---|---|---|---|---|---|
Clade | SNP distance, mean ± SD | No. of isolates within clade | CFM | CRO | Isolate collection year | Predominant MLST |
Clade A | 60.38 ± 28.55 | 278 | 259 | 63 | 2006–2017 | 1901 |
Clade B | 351.75 ± 202.12 | 64 | 11 | 11 | 2005–2017 | 1901 |
Clade C | 163.81 ± 112.1 | 151 | 32 | 0 | 2009–2016 | 9363 |
Clade D | 902.06 ± 508.36 | 25 | 6 | 4 | 2012–2017 | 7822 |
Clade E | 428.4 ± 161.29 | 23 | 4 | 2 | 2006–2017 | 1893 |
Clade F | 100.47 ± 79.75 | 15 | 3 | 8 | 2014–2017 | 7827 |
Clade G | 606.62 ± 325.5 | 44 | 10 | 6 | 2005–2017 | 1579 |
Clade H | 86.06 ± 127.66 | 42 | 1 | 2 | 2013–2017 | 7363 |
Clade I | 152.17 ± 101.66 | 25 | 1 | 0 | 2015–2016 | 5624 |
Clade J | 80.52 ± 47.57 | 20 | 3 | 5 | 2006–2016 | 1901 |
Clade K | 112.17 ± 76.83 | 21 | 1 | 1 | 2011–2015 | 1588 |
Clade L | 256.22 ± 231.76 | 9 | 0 | 0 | 2011–2016 | 10,932 |
Clade M | 222.03 ± 141.08 | 12 | 1 | 0 | 2012–2015 | 10,931 |
Clade N | 300.99 ± 226.17 | 36 | 0 | 0 | 2006–2016 | 1584 |
Clade O | 443.16 ± 247.37 | 11 | 0 | 0 | 2011–2014 | 1585 |
