Fig. 5: Deuteration scope: racemic acids.
From: Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
Reaction conditions: Substrate (0.40 mmol), crude enzyme powder (containing CvFAP about 20 mg), D2O (4 mL), DMSO or CH3CN (1 mL), 450 nm LED, 20 °C, 12 h. Yields and e.r. values were determined by chiral GC. D-inc. data were determined by 1H NMR or HRMS. E.r. value of 4e was calculated based on the conversion and e.r. of 4E.
