Fig. 3: Neutralization of B.1.1.7 and B.1.351 variants by BNT162b2 vaccinees’ sera and COVID-19 patient sera.

A Neutralization titres of initially seronegative vaccinees (n = 169) for D614G variants FIN-25 and SR121, and 85HEL (B.1.1.7) and HEL12-102 (B.1.351) variants before (0d), three (3wk), and six weeks (6wk) after the first dose of BNT162b2 vaccine and neutralization titres of convalescent sera of non-hospitalized patients (Conv, n = 50). Values above the groups indicate geometric mean titres (GMTs) and data are shown as geometric means and geometric SDs. Neutralization titres <20 were plotted as 10. B Neutralization titres 3 weeks (3wk) and six weeks (6wk) after the first dose of the vaccine. Statistical differences between the virus isolates were analyzed with Wilcoxon matched-pairs signed-rank test. Two-tailed p-values <0.05 were considered significant. Exact p-values were *=0.0201, **=0.0015, ****<0.0001 for 3wk and 6wk. Values above the groups indicate geometric mean titres (GMTs) and data are shown as geometric means and geometric SDs. Neutralization titres <20 were plotted as 10.