Fig. 3: Intercommunication between the photosynthetic network (X) and the metabolic network (Y) using hairpin stimulants.

a The mixture M consisting of constitutional dynamic networks CDNs X and Y subjected to the stimulant H_a leads to CDN Y-driven transition of the mixture into state M_a that includes CDN X_a and unaffected CDN Y. The cleavage of hairpin a (H_a) by CC′ of CDN Y leads to a fragmented strand H_a-1 that stabilizes AA′, resulting in the reconfiguration of CDN X into X_a (route I). Subjecting mixture M to hairpin d (H_d) leads to the photosynthetic network-guided transition of M into M_b through the cleavage of H_d by BB′ and the generation of a fragmented strand H_d-1 that stabilizes DD′, while CDN X is unaffected (route II). S and P represent substrate and product, respectively. b Time-dependent formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH) by the photosynthetic network at time intervals of treatment of mixture M with the stimulant H_a. For duplicate results in b, see Supplementary Fig. 23. c Time-dependent reduction of methylene blue by the metabolic network: (i) before and (ii) after treatment of mixture M with the stimulant H_a. d Time-dependent formation of l-alanine by CDN Y at time intervals of treatment of mixture M with the stimulant H_d. For duplicate results in d, see Supplementary Fig. 25. e Absorbance spectra of photosynthesized NADPH by CDN X: (i) before and (ii) after treatment of mixture M with the stimulant H_d. N = 2 independent experiments were performed. Source data are provided as a Source Data file.