Fig. 2: Structure and binding features of public antibodies to SARS-CoV-2 RBD. | Nature Communications

Fig. 2: Structure and binding features of public antibodies to SARS-CoV-2 RBD.

From: Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

Fig. 2: Structure and binding features of public antibodies to SARS-CoV-2 RBD.The alternative text for this image may have been generated using AI.

a The crystal structures of RBD and Fab complexes. RBD was colored in cyan. P22A-1D1 Fab was colored in slate and light blue, P5A-1D2 in hot pink and salmon, P5A-3C8 in yellow orange and light yellow, and P2C-1F11 (PDB ID: 7CDI) in violet and pink, for heavy chain and light chain, respectively. b The footprint of Fabs and ACE2 on SARS-CoV-2 RBD. The color of the epitope was depicted as in a. The epitope of ACE2 was colored by black. K417 was highlighted with blue. c Binding residues shared with ACE2 are listed. K417 was highlighted with blue box.

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