Fig. 2: Haemagglutination test to detect antibodies to RBD of the wild type (WT), B.1.1.7 and B.1.351 in patients who were naïve and previously infected following a single dose of the AZD1222.
From: Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
The HAT titres for the WT, B.1.1.7 and B.1.351 were measured in naïve individuals (n = 68) (blue) and previously infected individuals (n = 26) (red) 28–32 days following the vaccine (A). The HAT titres were measured in previously infected individuals at the baseline and following vaccination for the WT, B.1.1.7 and B.1.351 (n = 26) (B). The HAT titres were measured following a single dose in previously naïve individuals in different age groups (20–29 years = 13, 30–39 years = 25, 40–49 years = 8, 50–59 years = 13, >60 years = 9) (C). The black dotted line indicates the positive cut for the HAT. The Wilcoxon matched pairs signed-rank test was used to compare the means of the HAT titres before and after the vaccine. All tests were two sided. The Mann–Whitney U test (two tailed) was used to calculate the differences in the means in the HAT titres in the infected and naïve individuals. Data are presented as median values ± interquartile ranges as appropriate.
