Fig. 5: Directed acyclic graph (DAG) for Part 2 of the analysis showing the hypothesized relationships between early-life social experiences and %CCGG methylation. | Nature Communications

Fig. 5: Directed acyclic graph (DAG) for Part 2 of the analysis showing the hypothesized relationships between early-life social experiences and %CCGG methylation.

From: Early-life social experience affects offspring DNA methylation and later life stress phenotype

Fig. 5: Directed acyclic graph (DAG) for Part 2 of the analysis showing the hypothesized relationships between early-life social experiences and %CCGG methylation.

Potential confounding variables were modeled in three different context groups, which included demographic covariates (dark blue), early social experience covariates (dark green), and ecological covariates (light blue). *Maternal rank was considered a potential effect modifier of the associations of interest. Age at darting was included as a precision covariate. Variable positions over the timeline roughly corresponded with the timing of the assessment.

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