Fig. 1: Features of human chromosome 11p15.5-p15.4 region. | Nature Communications

Fig. 1: Features of human chromosome 11p15.5-p15.4 region.

From: Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects

Fig. 1

a Schematic representation of the key genetic elements in this study, ranging from 1.6 Mb to 3.0 Mb (hg19 assembly) from the telomere-end of chromosome 11. The purple and blue bars represent approximate extents of distinct TADs in this region (see Discussion). b The genetic features mentioned in this study, on human chromosome 11, from 1.7 Mb to 2.2 Mb (hg19 assembly). c The main 4C-seq contact pattern of the INS promoter in EndoC-βH1 cells. There is one major contact to the KRTAP5-6 region telomeric from the INS gene, whereas there are multiple major contacts to distal putative enhancers centromeric to the INS gene.

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