Fig. 5: The relative yields of heterologously expressed six natural products. | Nature Communications

Fig. 5: The relative yields of heterologously expressed six natural products.

From: Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria

Fig. 5: The relative yields of heterologously expressed six natural products.

Relative yields of heterologously expressed rhizomide A (a), holrhizin A (b), rhizoxins (c), icosalide A (d), and epothilones (e) and myxochelins (f) in E. coli GB05-MtaA (GB05), P. putida KT2440 (KT2440), DSM 7029 wild type (WT), and genome-reduced mutants (DTs). The BGCs were integrated into the genome by phiC31 site-specific recombination, respectively. Data are presented as mean values ± SD. n = 3 biologically independent samples. P values were determined by two-tailed unpaired t test. *p < 0.05; **p < 0.01; ***p < 0.001. Source data and the exact p values are provided as a Source Data file.

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