Fig. 5
From: Initiating polyketide biosynthesis by on-line methyl esterification
Selected initiation strategies involving on-line modification of the starter unit for modular PKSs34,35,36,37,38,39,40,41. a On-line modification initiation strategy for cis-AT PKSs. b On-line modification initiation strategies for trans-AT PKSs. ACP acyl carrier protein, AT acyltransferase, KS ketosynthase, KSQ decarboxylating ketosynthase, KR ketoreductase, DH dehydratase, MT methyltransferase, GNAT GCN5-related N-acetyltransferase, MAT malonyl-CoA: ACP acyltransferase, AMT amidotransferase.
