Table 2 The results of mixed-factorial ANOVA for the effect of tDCS on MEP amplitudes in early and late chronotypes.

From: Cognitive functions and underlying parameters of human brain physiology are associated with chronotype

Factor

df

F

P

ηp2

Age

1

0.898

0.351

0.032

Gender

1

0.001

0.996

0.001

BMI

1

1.728

0.199

0.060

Chronotype

1

0.743

0.396

0.026

Daytime

1

0.037

0.848

0.001

Stimulation (anodal,cathodal,sham)

1.196

0.585

0.478

0.021

Timepoint

4.206

1.113

0.354

0.039

Chronotype × daytime

1

8.632

0.007

0.242

Chronotype × stimulation

1.196

1.001

0.339

0.035

Daytime × stimulation

1.764

3.766

0.035

0.122

Chronotype × timepoint

4.206

1.564

0.185

0.054

Daytime × timepoint

4.066

0.529

0.716

0.019

Stimulation × timepoint

5.857

0.822

0.551

0.029

Chronotype × daytime × stimulation

1.764

55.098

<0.001

0.671

Chronotype × daytime × timepoint

4.066

1.382

0.244

0.048

Chronotype × daytime × stimulation × daytime

6.784

10.826

<0.001

0.286

  1. tDCS transcranial direct current stimulation, MEP motor-evoked potentials.
  2. Note: Individual averages of the normalized MEP were analyzed using a mixed-factorial design with repeated measures ANOVA (stimulation × timepoint × daytime × chronotype) with stimulation condition (anodal, cathodal, sham), timepoint (eight levels), and time of day (morning vs evening) as within-subject factors, chronotype (early vs late) as between-subject factor, and age, gender and BMI as covariates. In the case of significant ANOVA results, post hoc comparisons of MEP amplitudes at each timepoint were performed using Bonferroni-corrected post hoc t tests (two-sided). Significant effects are bold (where P < 0.05), n = 32 (16 per group).
Back to article page