Fig. 2: SARS-CoV-2 genome replication and RNA synthesis.
From: Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
A Cryo-tomogram slice of cell lamella depicting double membrane vesicles (DMVs) and vesicle packets (VPs). B Cryo-tomogram slice of a DMV at high magnification. Inset depicts detail of a DMV portal next to a virus assembly site, viewed at a different angle. C, D Portals on DMVs next to assembly sites. DMV double membrane vesicle, VP vesicle packet. Yellow arrows, DMV portals; blue arrows, viral assembly sites; red arrows, viral spikes. Scale bars are 500 nm in A, 100 nm in B, 50 nm in B inset, 100 nm in C, D.
