Fig. 1: ZTGC-DNA and conservation of the Z-cluster in Siphoviridae and Podoviridae phages. | Nature Communications

Fig. 1: ZTGC-DNA and conservation of the Z-cluster in Siphoviridae and Podoviridae phages.

From: Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA

Fig. 1: ZTGC-DNA and conservation of the Z-cluster in Siphoviridae and Podoviridae phages.

a Chemical structure of Z:T and G:C base pairs constituting S-2L’s ZTGC-DNA. b Genomic map of most important replication genes in all phages with close purZ and datZ homologues, and their phylogeny. The phages can be presently divided into four clades (colours in background to the left) with distinct organization and variants of replication-related genes. The names of these genes, identified by their colours, are shown below. Cyanophage S-2L is, until now, the only representative of its clade. Close scrutiny of the sequence data reveals possible mis-annotation of some viral sequences with bacterial names (“ann.?” note) – their length and content perfectly match other viral sequences.

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