Fig. 5: The second- and third-layer networks of module M4 containing no QTL.
From: Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
a Left panel: The 464-node inter-submodule network at the second layer under network community M4 of the first-layer network. Right panel: Distribution of the number of outgoing and incoming links over 464 submodules whereas one of the leaders SM437 is indicated. Within the distribution plot, two smaller plots show the power distribution of the frequency of outgoing and incoming links. b The 24-node inter-SNP network at the third later under leader submodule SM437 of the second-layer network M4. c Interaction network among proteins (with names indicated) annotated from SNP network, where the strength of protein interaction is proportional to the thickness of linked line. d Curves of genetic effects on phenotypic plasticity for insignificant SNPs chosen from the third-layer network in (b). Net genetic effect (blue line) is decomposed into independent effect (red line) and dependent effects (green line) due to regulation by other SNPs.
