Fig. 5: m6Am and 5′-UTR m6A are dynamically regulated by different stress conditions.
From: m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
a–d Volcano plot showing stress-induced m6Am and 5′-UTR m6A: heat shock-inducible m6Am peaks (a) and 5′-UTR m6A peaks (b), and hypoxia-inducible m6Am peaks (c), and 5′-UTR m6A peaks (d). Red circles denote stress-upregulated peaks; blue circles denote stress-downregulated peaks. Representative views of elevated m6Am peaks in CHOP (e) and GLUT1 (f) under hypoxia stress. Representative views of elevated 5′-UTR m6A peaks in TP53 (g) and PTEN (h) under hypoxia stress. Pink and blue background colors denote m6Am and m6A signals, respectively.
