Fig. 2: Structural locations of the spike mutations of lineage B.1.526.
From: Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York
a Side and top views of the SARS-CoV-2 spike trimer (PDB 7JJI) with mutations of lineage B.1.526 shown as spheres. b–g Models of representative neutralizing antibodies (cartoon, VH-VL domain only) bound to RBD (b–f, gray surface) or NTD (g, wheat surface). Sites for B.1.526 lineage mutations are shown as red spheres, N-linked glycans are shown in cyan. The S477N site is also shown (label outlined) for the branch containing this mutation instead of the E484K mutation (see Fig. 1); b Class 1 (PDB 7K8M); c Class 2 (PDB 7K8S); d Class 3 (PDB 7K8Z); e Class 4 (PDB 6W41); f Class 58; g NTD-specific antibody 4A8 (PDB 7C2L).
