Fig. 6: Synthetic applications. | Nature Communications

Fig. 6: Synthetic applications.

From: Difluorocarbene enables to access 2-fluoroindoles from ortho-vinylanilines

Fig. 6: Synthetic applications.The alternative text for this image may have been generated using AI.

Reaction conditions: a12 or 15 (0.2 mmol), 2a (3 equiv., 0.6 mmol), K3PO4 (3 equiv.), H2O (0.1 mL), CH3CN (2 mL) under 90 °C for 12 h, N2. b12a (5 mmol), 2a (3 equiv., 15 mmol), K3PO4 (3 equiv.), H2O (1.5 mL), CH3CN (25 mL) under 90 °C for 24 h, N2. c4a (5 mmol), 2b (3 equiv., 15 mmol), K2CO3 (3 equiv.), H2O (1.5 mL), CH3CN (25 mL) under 90 °C for 24 h, N2.

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