Fig. 5: Cycloheximide (CHX) does not explain the poor correlation between various datasets in humans. | Nature Communications

Fig. 5: Cycloheximide (CHX) does not explain the poor correlation between various datasets in humans.

From: Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments

Fig. 5: Cycloheximide (CHX) does not explain the poor correlation between various datasets in humans.The alt text for this image may have been generated using AI.

Correlation analysis of transcriptome-wide A-site codon occupancy across data from this study and published datasets for human cells (HEK 293 and HEK 293T cells) using different CHX treatments19, 20, 58,59,60,61,62,63. The solid line depicts the fitted line and shaded areas represent 95% confidence intervals for three biological replicates (n = 3). Each black dot represents a codon. The size of the box indicates p-value. Correlations with a p-value > 0.05 are crossed out.

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