Fig. 3: Heterogeneous, hierarchical, biomimetic 3d nanostructures using functionalized recombinant spider silk proteins.
From: 3D electron-beam writing at sub-15 nm resolution using spider silk as a resist
a Schematic representation of a natural spider web with heterogeneous and hierarchical structures. b, c x–y plane controllable configuration of spider nanowebs for PMMA nanospheres (~250 nm in diameter) selective adhesion. Scale bars in (c), fluorescence microscope photographs (lower left 3 images), 5 μm; false-color SEM image (lower right), 1 μm. d, e z direction controllable configuration of spider nanowebs for single brain tumor cell (~30 μm in diameter) adhesion. Scale bar in (e), fluorescence microscope photographs (lower row), 10 μm. f Genetically engineered spider silk proteins functionalized with RFP (red fluorescent protein) and fluorescein sodium. R: Arginine. S: Serine. P: Proline.
