Fig. 2: Microglial cells contact nodes of Ranvier in human central nervous system. | Nature Communications

Fig. 2: Microglial cells contact nodes of Ranvier in human central nervous system.

From: Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

Fig. 2

A Immunohistostainings of post-mortem human hemispheric white matter tissue (healthy donor) showing microglial cells (blue, resident microglia, TMEM119) contacting nodes of Ranvier (NaV, brown). B, C Immunofluorescent stainings of post-mortem human hemispheric white matter tissue (healthy donor) showing microglial cells (green; B, resident microglia, TMEM119, and C, homeostatic microglia, P2Y12R) contacting nodes of Ranvier (NaV, red). Bii, Cii 3D reconstructions correspond to the boxed area in Bi and Ci respectively. Scale bars: (2D) A, B, C 10 μm; (3D), B, C 2 μm. A: n = 6 samples, B, C: n = 5 samples.

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