Fig. 1: Overview of ESCC ecosystem characterized by scRNA-seq.
From: Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis
a Scheme of the overall study design. b, c tSNE plots of 97,631 CD45- cells (b) and 111,028 CD45+ cells (c), colored by cell type (left) and tissue type (top right). The proportions of cell types in normal and tumor tissues are shown on the bottom right (colors as in the left panel). Cell types that significantly increase (solid line filled with color) or decrease (dashed line) in tumor tissue (two-sided Wilcoxon test, P < 0.05) are indicated by links between normal and tumor bars. P values: 0.001 (epithelial cell), 0.001 (fibroblast), 0.010 (pericyte).
