Fig. 6: The DNA-binding channel is a common target for transcription inhibition in all domains of life.
From: Structural basis of RNA polymerase inhibition by viral and host factors
The structures of the RNAP from a E. coli (pdb code 4lk06), b S. acidocaldarius, and the c S. cerevisiae RNAPIII (pdb code 6tut36) are all shown in grey ribbons with the clamp and rudder highlighted in light orange and yellow, respectively. a The viral inhibitor T7 Gp2 is shown in green, b RIP from ATV in blue, and c the cellular negative regulator MAF1 in magenta.
