Fig. 2: Copy number alterations in our cohort. | Nature Communications

Fig. 2: Copy number alterations in our cohort.

From: Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer

Fig. 2: Copy number alterations in our cohort.

a Arm level CNVs identified by GISTIC2.0 in SCLC (n = 40). False discovery rate (FDR) corrected p value represents significant changes from Benjamini–Hochberg testing. b The genome chromosome plots depict significant cytobands identified by GISTIC2.0. c The significant somatic focal CNVs of pure SCLC and combined lung cancer are shown for each region of the individual patient. Cytobands with genes involved in cosmic drivers and those that occurred in at least 50% of patients are shown. d Counts in the trunk and branch of CNVs for each patient; Percentage of branch CNVs for each patient (n = 40). SCLC small cell lung cancer, Amp amplification, Del deletion, CNVs copy number variations.

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