Table 1 Baseline characteristics in all patients infected with SFTSV.

From: A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome

Variables

Recovered patients (n = 30)

Deceased patients (n = 11)

P value

Age, years

63.6 (56.2–71.1)

65.4 (62.7–71.3)

0.494

Males, %

18 (58.1%)

6 (60.0%)

0.914

Duration, daysa

19.0 (16.0–24.3)

10.0 (8.0–11.0)

1.80 × 10−5

SFTSV, IU/mLb

1.66 × 104

(5.60 × 102−2.28 × 105)

3.67 × 106

(4.01 × 105−3.83 × 107)

4.961 × 10−4

Complete blood count

  

WBC, ×109/ L

3.46 (1.90–4.35)

2.75 (1.68–7.17)

0.976

Neutrophil, ×109/L

1.87 (1.20–3.81)

1.15 (0.73–5.15)

0.564

Lymphocyte, ×109/L

0.60 (0.46–1.04)

0.76 (0.50–1.67)

0.387

RBC, ×1012/L

4.12 (3.88–4.47)

3.61 (3.42–4.26)

0.029

Hemoglobin, g/L

129.0 (118.6–140.0)

120.0 (104.8–141.0)

0.274

Platelet, ×109/L

43.0 (22.0–55.0)

35.0 (14.0–45.8)

0.261

CRP, mg/L

3.60 (2.19–18.30)

8.96 (6.07–11.84)

0.351

Coagulation

   

PT, s

11.60 (10.60–12.20)

12.10 (11.63–12.70)

0.164

APTT, s

37.20 (33.00–44.40)

63.50 (47.40–66.75)

2.368 × 10−4

Liver function

   

ALT, U/L

88.0 (47.0–147.0)

142.00 (108.5–191.5)

0.033

AST, U/L

221.0 (108.0–486.0)

825.00 (459.0–1299.5)

1.132 × 10−3

TBIL, μmol/L

10.20 (7.80–13.40)

10.30 (9.40–22.80)

0.315

Renal function

   

BUN, mmol/L

5.04 (3.70–6.72)

7.95 (4.83–12.55)

0.022

Creatinine, μmol/L

68.0 (62.60–84.40)

90.00 (70.50–145.80)

0.041

  1. Data are median (IQR) or n (%). P values were calculated by two-sided Mann–Whitney U test or χ² test.
  2. WBC white blood cell, RBC red blood cell, CRP C-reactive protein, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, BUN blood urea nitrogen.
  3. aDuration was defined as days from onset to outcomes.
  4. bIU indicates 50% tissue culture infective dose (TCID50), 10x TCID50/mL = 0.496 × 10x+3 copies/mL. Statistic analysis was performed with log10-transformation of SFTSV viral load.
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