Fig. 4: Spleen and kidney injury during BALB/c mice infection with MASCp36.
From: Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
a H&E staining of spleen sections from male BALB/c mice (9-month-old) infected with MASCp36 (n = 3 per group). b Multiplex immunofluorescence staining of mouse spleen sections for detection of CD19 (green) B cells, CD3 (magenta) T cells, and ICOS (white) follicular helper T cells (n = 3 per group). c H&E staining of kidney sections from male BALB/c mice (9-month-old) infected with MASCp36 at 4 dpi (n = 3 per group). d Multiplex immunofluorescence staining of mouse kidney sections for CD31(white) and PDPN (green) (n = 3 per group). The yellow and red arrows indicate discrete glomerular basement membrane and endothelial vessels, respectively.
