Fig. 3: Single-cell transcriptome atlas from non-retina cells in the human eye. | Nature Communications

Fig. 3: Single-cell transcriptome atlas from non-retina cells in the human eye.

From: Multi-species single-cell transcriptomic analysis of ocular compartment regulons

Fig. 3

a tSNE plot visualisation of cells obtained from scleral and choroid layers of the eye. Five transcriptionally distinct clusters were observed. b tSNE plot visualisation of cells obtained from the cornea of the eye. Seven transcriptionally distinct clusters were observed. c tSNE plot visualisation of cells obtained from iris pigmented epithelium, iris muscle, and stromal region of iris. Seventeen transcriptionally distinct clusters were observed in the iris region of the eye. d Selecting highly variable interacting pairs that exhibited high cell type-to-cell type variation in the dataset. e Hierarchical clustering of similar cell–cell signalling probability scores and visualised on a tSNE plot. f Global cell–cell interaction map across cell type of the eye. Edge weights represent the probability of signalling between cell clusters.

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