Fig. 6: Trip6 deletion affects ciliogenesis but not cell-cell adhesion.

Immunofluorescence microscopy-based expression and localization analysis of cilia (CLUAP1) and cell-cell adhesion (β-CATENIN) markers, as well as of TRIP6, in the LV of control (trip6+/−) and trip6−/− mouse brain. Their comparison demonstrates TRIP6 deletion and ciliation defects in trip6−/− specimens, but no obvious adhesion defects. Magnification panels depict selected areas (indicated by white frames in the low magnification images), re-oriented with the ventricular lumen positioned at the lower part of each image. Epn ependyma, Chp choroid plexus. Scale bar: 50 μm.