Table 1 AA substitutions detected in the spike protein of VOCs B.1.1.7 (EPI_ISL_601443) and B.1.351 (EPI_ISL_678615) compared to Wuhan-Hu-1 (NC_045512).

From: ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7

Substitution (Wuhan AA numbering)

VOC B.1.1.71

VOC B.1.3513

L18F

−

+

HV69-70del

+

−

D80A

−

+

Y144del

+

−

D215G

−

+

LAL242-244del

−

+

K417N

−

+

E484K

−

+

N501Y

+

+

A570D

+

−

D614G

+

+

P681D

+

−

A701V

−

+

T716I

+

−

S982A

+

−

D1118H

+

−