Fig. 2: Rictor deficiency results in defective innate and adaptive immune responses.
From: mTORC2 confers neuroprotection and potentiates immunity during virus infection
a A graph representing corneal thickness of HSV-1 infected mice, quantified from H and E stained tissue sections, (n = 3). b Graph representing the cell count per section area for HSV-1 infected cornea of mice, quantified from H and E stained tissue sections (n = 3). c–h Graph representing population of respective immune cells in HSV-1 infected eye at 10 dpi, (n = 7). i Immunohistochemistry staining of CD8+ cells in HSV-1 infected corneal tissue. Data is the representative of five independent experiments. Scale bar- 50 µm. j Schematics of neutralization assay. k Graph showing neutralizing antibody response from serum collected at 10 dpi (n = 5 per group). Multiple t-test was performed assuming individual variance for each row. l Cytokine analysis of lymph node and m brain stem tissue of HSV-1 infected animals at 10 dpi (n = 5). Two-tailed unpaired t-test was used to analyze the data presented in a–h. Data are represented as mean ± SEM in a–h and k. Source data underlying Fig. 2k–m are provided as a Source Data file.
