Fig. 4: Modeling of surface SAS-6 self-assembly.

a Fit with coagulation-fragmentation model (overlaid thick lines) of the experimental evolution over time of SAS-6 assembly reaction from Fig. 3c. b, c Model predictions of average ring formation efficiency (b) and average ring symmetry (c) at varying Kd and SAS-6 homodimers/μm2. d Fraction of closed rings of indicated symmetries calculated as numerical solution of the fitted model after 17 min as a function of closed lifetime (1 = experimental values, <1 slower opening, >1 faster opening).