Fig. 4: Modeling of surface SAS-6 self-assembly. | Nature Communications

Fig. 4: Modeling of surface SAS-6 self-assembly.

From: Kinetic and structural roles for the surface in guiding SAS-6 self-assembly to direct centriole architecture

Fig. 4

a Fit with coagulation-fragmentation model (overlaid thick lines) of the experimental evolution over time of SAS-6 assembly reaction from Fig. 3c. b, c Model predictions of average ring formation efficiency (b) and average ring symmetry (c) at varying Kd and SAS-6 homodimers/μm2. d Fraction of closed rings of indicated symmetries calculated as numerical solution of the fitted model after 17 min as a function of closed lifetime (1 = experimental values, <1 slower opening, >1 faster opening).

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